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For those on a plant-based diet, fortified foods or supplements may be necessary to meet B12 requirements

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The article says evidence suggests estrogen modulates GLP-1 receptor expression in hypothalamic appetite centres, so as estrogen falls, GLP-1 signalling efficiency may diminish and compound existing metabolic challenges

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The exception is that Zepbound is FDA-approved to treat excess weight and obesity and Mounjaro is FDA-approved to treat type 2 diabetes